For Healthcare Providers

Re-Awaken Skin From Within

With love from
your future self

Imagine skin that’s resilient and authentically you—a gift to your future self. RADIESSE is the #1 researched biostimulator, proven to firm, tighten, and reverse visible signs of aging from within.

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WHAT IS RADIESSE?

With RADIESSE, every day is a love letter from your future self

RADIESSE works with your body, activating skin’s regenerative power to boost collagen, elastin, and other key proteins. It restores skin quality and function from the inside out—delivering firmer, more elastic skin that looks healthier and more resilient over time. 

But don’t just take our word for it. Take a look at the difference RADIESSE has made for real people.

Actual patient. Individual results may vary.
Actual patient. Individual results may vary.

Maureen, 69

Treatment Plan

Maureen received two RADIESSE treatments using a 1:2 saline dilution. Following the initial treatment at baseline, she received a second treatment at a 6-week follow-up appointment. These results were captured 6 months after the start of her treatment plan.

Before & After Results

Maureen’s RADIESSE Experience

Watch as Maureen shares her personal journey with RADIESSE, from noticing the first signs of aging on her chest to regaining firm, youthful-looking skin that her friends and family can’t stop complimenting.

Hi, my name is Maureen Cashin. Everyone calls me Mo. I am 67 years old. I was a Production Manager for a television network. I was treated on my décolletage, as they say, and I’m telling you, the results are amazing.

So I noticed some wrinkles from a lot of sun damage, and I had a lot of lines going all over the place, and the RADIESSE just sort of took it all away. Smoothed it up, zhushed it up. Well before, I was just creepy chest and sun damage, and after I really was very impressed with it. I couldn’t stop looking at it. I’m like, wow, what a difference.

My husband of 43 years recognized it two weeks after. I was shocked. He’s like, yeah, I see the difference. And I was like, who are you? Where have you been all my life.

Most of my friends recognize it as well. I was at my Pilates class and my instructor pulls me over. She’s like Mo, what did you do? And I explained to her what it was and I was a little hesitant because I’m like, oh, do I tell them that I did this? And they were all huddled around my phone looking at the before and afters.

I went to a wedding in June and I wore a dress that was low cut. And I did that specifically to show off my less wrinkled chest.

I did buy a differen bathing suit this year. A little lower. I’m just showing it off. RADIESSE made me feel when I was trying on clothes, look in the mirror and go, what?!

My favorite thing about growing older is waking up every day and leave nothing on the table every day. I go for it every single day. My husband, we’re on the same page all the time. I’m Maureen, and I’m a firm believer in RADIESSE.

RADIESSE delivers natural looking results that last. It just looks like me with visibly smoother and tighter skin. Looking your best starts with your skin.

RADIESSE benefits: FIRMS, TIGHTENS, REVERSES

Rebuild foundational elements of your skin

True skin strength starts deep beneath the surface. RADIESSE activates skin’s regenerative power, delivering measurable improvements in skin quality and reversing the visible signs of aging.

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Three diverse women with firm, radiant skin illustrating anti-aging skin treatment results.
Actual patients. Individual results may vary.

What my future self will thank me for

REAL PATIENT RESULTS WITH RADIESSE

“RADIESSE helps support collagen and elastin production over time, so this felt like the perfect next step in my wellness journey!”

Kam Williams
RADIESSE Patient

REGENERATIVE SKIN SCIENCE

How RADIESSE works

What is happening under the skin as we age? And why does a non-inflammatory pathway matter for biostimulation? Discover this and more as you dive into the science behind RADIESSE. 

Regenerate With RADIESSE
Woman outdoors smiling and touching her face
Actual patient. Individual results may vary.
Man with smooth, healthy-looking skin touching his face
Actual patient. Individual results may vary.

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Common questions

RADIESSE and RADIESSE (+) are dermal fillers that are FDA-approved to smooth moderate to severe facial wrinkles and folds, such as nasolabial folds (the creases that extend from the corner of your nose to the corner of your mouth).1,2 RADIESSE is also used for correcting volume loss in the back of the hands.3

RADIESSE is injected under the skin in a quick procedure that can be done over the lunch hour.1 

Restoration of volume and smoothing of the appearance of wrinkles and lines are visible immediately after a RADIESSE treatment.1,4 Over time, RADIESSE stimulates the production of collagen5-9 and elastin,6-8,10 supporting continued improvement in skin quality.7 Results have been shown to last up to 2 years.11

Yes. RADIESSE® is the first and only injectable biostimulator in the U.S. FDA-approved to treat both the face and specific areas of the body. Beyond correcting facial wrinkles and folds, RADIESSE is specifically indicated to restore volume to the back of the hands. By using a specialized 1:2 dilution for the chest area, RADIESSE can also be used to improve the appearance of wrinkles in the décolleté (chest) in patients 22 years and older.

More Frequently Asked Questions

References:
1. Radiesse [Instructions for Use]. Franksville, WI: Merz North America, Inc; 2023. ​
2. Radiesse (+) [Instructions for Use]. Franksville, WI: Merz North America, Inc; 2023. ​
3. Radiesse for Hands [Instructions for Use]. Franksville, WI: Merz North America, Inc; 2023. ​
4. Tzikas TL. Dermatol Surg. 2008;34(suppl 1):S9-S15. ​
5. Yutskovskaya Y, et al. J Drugs Dermatol. 2014;13(9):1047-1052. ​
6. Yutskovskaya YA, et al. J Drugs Dermatol. 2017;16(1):68-74. ​
7. Yutskovskaya YA, et al. J Drugs Dermatol. 2020;19(4):405-411. ​
8. Nowag B, et al. CaHA microspheres: contact with fibroblasts and amount of spheres are key factors for collagen stimulation. Presented at: AMWC 2020; Monte Carlo, Monaco; April 2-4, 2020.​
9. Aguilera SB, et al. Aesthet Surg J. 2023;43(10):1063-1090.​
10. González N, et al. Dermatol Surg. 2019;45(4):547-551. ​
11. Bass LS, et al. Aesthet Surg J. 2010;30(2):235-238.

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Ready to re-awaken your skin from within?

Find a provider in your area and book a consultation to see if RADIESSE is right for you.

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Diverse group of women smiling with healthy-looking skin.

Actual patients. Individual results may vary.

What are RADIESSE® and RADIESSE® (+)?

RADIESSE® and RADIESSE® (+) are dermal fillers that are used for smoothing moderate to severe facial wrinkles and folds, such as nasolabial folds (the creases that extend from the corner of your nose to the corner of your mouth).

RADIESSE® is also used for correcting volume loss in the back of the hands and, when diluted with saline to smooth away wrinkles such as those in the décolleté in patients 22 years of age and older. RADIESSE® (+) is also used for improving moderate to severe loss of jawline contour in adults over 21 years old.

RADIESSE® and RADIESSE® (+) IMPORTANT SAFETY INFORMATION

Who should not use RADIESSE® or RADIESSE® (+)?

You should not use RADIESSE® or RADIESSE® (+) if you have an allergy to any component of the product, if you have a history of severe allergies, if you have a bleeding disorder. You should not use RADIESSE® (+) if you have an allergy to lidocaine or medicines like it.

What is the most important information I should know about RADIESSE® and RADIESSE® (+)?

One of the risks with using these products is unintentional injection into a blood vessel. The chances of this happening are very small, but if it does happen, the complications can be serious, and may be permanent. These complications, which have been reported for facial injections, can include vision abnormalities, blindness, stroke, temporary scabs, or permanent scarring of the skin. If you have changes in your vision, signs of a stroke (including sudden difficulty speaking, numbness or weakness in your face, arms, or legs, difficulty walking, face drooping, severe headache, dizziness, or confusion), white appearance of the skin, or unusual pain during or shortly after treatment, you should notify your health care practitioner immediately.

As with all procedures that involve an injection through the skin, there is a risk of infection.

Do not use RADIESSE® or RADIESSE® (+) if you have a skin infection until it has healed.

It is not known if RADIESSE® or RADIESSE® (+) is safe or effective in the lips, or in the area around the eyes, or if you are pregnant or breastfeeding. 

It is not known if RADIESSE® or RADIESSE® (+) is safe or effective beyond 3 years in the face, 1 year in the hand, and 84 weeks in the décolleté.

Injection of RADIESSE® (+) into the jawline may temporarily alter jaw function.

The safety of RADIESSE® in the décolleté in patients under 22 years of age has not been established.

The microspheres in RADIESSE® and RADIESSE® (+) can be seen in X-rays and CT scans. It is very important that you tell your health care provider that you have had RADIESSE® or RADIESSE® (+) dermal filler. A clinical study found no evidence of RADIESSE® injected in the décolleté being visible on mammograms or breast ultrasounds, but you should still inform your doctor and radiologist that you have received RADIESSE® in the treated area so they can interpret your imaging appropriately.

If you have a history of herpes, you may experience a herpes breakout after receiving RADIESSE® or RADIESSE® (+).

Injection in the back of the hand may result in temporary difficulty performing activities. RADIESSE® may cause nodules, bumps or lumps in the back of the hand and can last up to 1 year.

You should minimize strenuous activity and avoid extensive sun or heat exposure for about 24 hours after treatment and until any swelling or redness has resolved.

What should I tell my doctor before using RADIESSE® or RADIESSE® (+)?

Tell your health care provider if you are taking blood thinners or medicines that can interfere with the clotting of blood, such as aspirin or warfarin. These medicines might make it more likely that you will experience bruising or bleeding at the injection site. Tell your health care provider if you have any diseases, injuries or disabilities of the hand, if you have a history forming large, raised scars or if you have had any other skin treatments such as skin peels.

What are the most common adverse events with RADIESSE® or RADIESSE® (+)?

The most common adverse events seen in clinical studies of RADIESSE® used in the hands include bruising, redness, swelling, pain, itching, nodules or bumps/lumps, difficulty performing activities, loss of sensation and other local side effects. The most common adverse events seen in clinical studies of RADIESSE® or RADIESSE® (+) used in the face include bruising, redness, swelling, pain, itching, difficulty chewing, and other local side effects.

Delayed-onset inflammation near the site of injection is one of the known adverse events associated with dermal fillers. Cases of delayed-onset inflammation have been reported to occur at the treatment site following viral or bacterial illnesses or infections, vaccinations, or dental procedures. Typically, the reported inflammation was responsive to treatment or resolved on its own.

These are not all of the possible side effects with RADIESSE® or RADIESSE® (+). Merz collects information about adverse events seen with RADIESSE® and RADIESSE® (+) outside of clinical studies. These events are included in the RADIESSE® and RADIESSE® (+) Patient Information Guide based on an assessment of seriousness and potential causal relationship to RADIESSE® or RADIESSE® (+). Please see the Patient Information Guide available at www.radiesse.com for list of these events. Tell your health care provider about any side effects that bother you or do not go away.

Important: For full safety information, please visit www.Radiesse.com or call MyMerz Solutions at 1-844-469-6379

RADIESSE® and RADIESSE® (+) are available by prescription only.